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sc 283467  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology sc 283467
    Sc 283467, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sc+283467/2%E2%80%B2-C-Methyladenosine/bio_rxiv__2025__05__14__654103-196-11-12
    Average 93 stars, based on 12 article reviews
    sc 283467 - by Bioz Stars, 2026-09
    93/100 stars

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    Article Title: Mitochondria-derived dsRNA-induced stress granules promote IRF3-mediated fibrotic responses
    Article Snippet: For TGFβ stimulations, cells were given fresh culture media ± 5 ng/mL TGFβ1 (7666-MB-005, R&D, Minneapolis, MN) for indicated lengths of time. .. For pharmacologic inhibitor experiments, cells were pre-treated with 25 μM EGCG (4143, Sigma, St. Louis, MO) for one hour or 50 μM 2-CM (sc-283467, Santa Cruz, Dallas, TX) or DMSO vehicle control (N182, VWR, Radnor, PA) for 24 hours prior to TGFβ stimulation. .. After plating in 6-well or 12-well plates, cells were transfected the same day with scrambled control siRNA (sc-37007, Santa Cruz, Dallas, TX) or a pool of three siRNAs against human IRF3 (encodes IRF3 protein) (SR320690, Origene, Rockville, MD) or human IFNAR (encodes Type I interferon receptor) (sc-35637, Santa Cruz, Dallas, TX) using Lipofectamine RNAiMAX transfection reagent following the manufacturer’s instructions.



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